Prävention & Genetik

Prof. Dr. Günter Emons

Stadler Z et al. Targeted therapy based on germline analysis of tumor-normal sequencing (MSK-IMPACT) in a pan-cancer population.
Cobain E et al. Tumor/normal genomic profiling in patients with metastatic solid tumors identifies pathogenic germline variants of therapeutic importance.
Watson C et al. The prevalence of germline mutations among patients with solid tumors with genomic alterations identified on tumor testing: Results from a tertiary care academic center molecular tumor board.
Khan S et al. Potential germline findings identified during somatic tumor testing: Room for improvement.

Dr. Kerstin Rhiem

Thomas S et al. The impact of tumor NGS testing on hereditary cancer risk assessment and population management in an integrated community health care system.
Waterhouse D et al. First year outcomes of an initiative to increase BRCA testing among NCCN guideline-eligible breast cancer patients within a large community OCM practice.
Shelton C et al. Population genetic screening for hereditary breast and ovarian cancer in at-risk patients: A novel testing and prevention model for community hospitals reveals high mutation rates rurally.
Gonzalez R et al. Genetic counseling referrals after next generation sequencing testing.

Prof. Rita Schmutzler

Bolton K et al. The impact of poly ADP ribose polymerase (PARP) inhibitors on clonal hematopoiesis.
Wu H et al. Characterization of clonal hematopoiesis of indeterminate potential mutations from germline whole exome sequencing data.
Comen E et al. Evaluating the association between clonal hematopoiesis and germline pathogenic and likely pathogenic variants in cancer predisposition genes.
Weitzel J et al. Clinical conundrums: Developing a strategy for discerning TP53-associated chip and coherent clinical care.

Prävention & Genetik Highlights

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